SHI YI,LIPARI JOHN M,PADDEN BRIAN E,SPENCE JULIE K,DIAS LLOYD S.
申请号:
CL2014001548
公开号:
CL2014001548A1
申请日:
2014.06.12
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
A composition comprises a kinase inhibitory compound, e.g., N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N′-(3-fluorophenyl)urea, in a mixture comprising (a) a pharmaceutically acceptable water-soluble polymeric carrier and (b) a pharmaceutically acceptable surfactant. The composition is suitable for dilution with an IV solution for administration to a subject in need thereof for treatment of a cancer.COMPOSICION QUE COMPRENDE A) N-(4-{4-AMINO-7-[1-(2-HIDROXIETIL)-1H-PIRAZOL-4-IL]TIENO[3,2-C]PRIRIDIN-3-IL}FENIL)-N'-(3-FLUOROFENIL)UREA O UNA SAL, B) POLIETILENGLICOL, C) ACEITE DE RICINO POLIOXIETILADO Y D) ETANOL; Y SU USO PARA TRATAR EL CANCER.