The present invention provides a kind of oral administration medical composition containing FTD and TPI that can be administered orally stable under high humidity conditions. The oral administration medical composition contains α, α, and α-trifluorothymidine and the chloro- 6- of 5- (2- lminopyrrolidine -1- base) methyl -2,4 (1H, 3H)-hybar X hydrochloride as effective component, contain 25 as excipient. The additive that critical relative moisture when C is 85% or more.本發明提供一種即使在高濕度條件下也穩定的能夠口服給藥的含有FTD和TPI的口服給藥用醫藥組合物。該口服給藥用醫藥組合物含有α,α,α-三氟胸苷和5-氯-6-(2-亞氨基吡咯烷-1-基)甲基-2,4(1H,3H)-嘧啶二酮鹽酸鹽作爲有效成分,作爲賦形劑含有25。C時的臨界相對濕度爲85%以上的添加劑。