Young-Bae PARK,Hyo-Soo KIM,Hyun-Jae KANG,Jin HUR,Jeehoon KANG,Jung-Kyu HAN,Ji-Yeon YUN,Jae-Il CHOI,Jin-A KANG
申请号：
US14896336
公开号：
US20160151419A1
申请日:
2014.06.05
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present application discloses a method for producing peripheral blood stem cells with improved angiogenic properties through EPO or APS priming, and a use thereof. The cells produced according to the method of the present application induce angiogenesis, and thus can be effectively used for the regeneration of, or recovery from, various diseases requiring facilitation of angiogenesis, such as ischemic diseases occurring in the muscle, brain, heart, kidney, or large intestine, e.g. tissue damage, cerebral infarction, stroke, reperfusion injury, myocardial infarction, congestive heart failure, peripheral vascular obstruction, cardiac hypertrophy, low heart contraction, low heart dilatation, maladaptive cardiomegaly, systolic heart failure, diastolic heart failure, hypertensive heart failure, artery or mitral valve diseases, heart blood vessels with pulmonary valve diseases, or ischemic heart blood vessels, caused by ischemia.
