PROBLEM TO BE SOLVED: To provide a hollow fiber microporous membrane capable of developing sufficient blood plasma leak resistance and stable and excellent gas exchange capacity even in long-term continuous use, and an oxygenator having the same incorporated therein.SOLUTION: The hollow fiber microporous membrane, which comprises a hydrophobic material of which the oxygen gas flux is 10×10-3-500×10-5 [cm3 (STP)/cm2/sec/cmHg] and the ethanol flux is 2-80 [ml/min/m2] and which has open cells with a mean pore radius of 0.008-0.07 &mum, and the oxygenator having the same incorporated therein have excellent oxygen and carbon dioxide exchange capacity and blood plasma leak resistance enabling continuous use over long period of time of one week or more as compared with a conventional microporous membrane and an oxygenater having the same incororated therein.COPYRIGHT: (C)2002,JPO【課題】 長期の連続使用に於いても充分な耐血漿リーク性と安定し優れたガス交換性能を発揮できる中空糸微多孔膜、それを組み込んだ人工肺を提供すること。【解決手段】 酸素ガスフラックスが10×10-5~500×10-5[cm3(STP)/cm2/sec/cmHg]であり、エタノールフラックスが2~80[ml/min/m2]であり、平均孔半径0.008~0.07μmの連通孔を有する疎水性の素材からなる中空糸微多孔膜及びそれを組み込んだ膜型人工肺は従来の微多孔膜及びそれを組み込んだ膜型人工肺に比べて、優れた酸素及び炭酸ガス交換性能を有し、かつ1週間以上の長期の連続使用が可能な耐血漿リーク性を備えることを見出した。
