GlaxoSmithKline Intellectual Property Development Limited
发明人:
Zehong Wan,Yingxia Sang,Qing Zhang
申请号:
US14161837
公开号:
US09051325B2
申请日:
2014.01.23
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to bicyclic[5,6]imidazo pyrimidone compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.In one aspect, this invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof,wherein different R groups are defined in the patent application.