In accordance with one embodiment, a method for determining changes in health of a user is disclosed. The method includes sensing multi-dimensional motion of a body part of a user to generate a first multi-dimensional motion signal at a first time and date in response to the first multi-dimensional motion signal, generating a first neuro-mechanical fingerprint generating a first health measure in response to the first NFP and user calibration parameters sensing multi-dimensional motion of the body part of the user to generate another multi-dimensional motion signal at another time and date in response to the another multi-dimensional motion signal, generating another neuro-mechanical fingerprint generating another health measure in response to the another NFP and the user calibration parameters and comparing the first health measure with the another health measure to determine a difference representing the health degradation of the user.