DEKELVER RUSSELL,GUPTA MANJU,MILLER JEFFREY C,NOVAK STEPHEN,PETOLINO JOSEPH F
申请号:
NZ59935110
公开号:
NZ599351A
申请日:
2010.10.22
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
599351 Disclosed is a synthetic or recombinant zinc finger protein that modulates expression of a &bgr;-ketoacyl-ACP synthetase (KAS) gene, wherein the zinc finger protein comprises five or six zinc finger recognition regions designated and ordered F1 to F5 for a five finger protein or F1 to F6 for a six finger protein, as shown in a single row of Table 1, wherein the zinc finger protein binds to a target site in the KAS gene. ZFP F1 F2 F3 F4 F5 F6 13685 RSDNLSV QKINLQV RSDTLSE TRSSRIN RSDALAR N/A 13714 RSDHLSA TSSSRIN RSDNLAR DRSHLAR RSDNLSE RNAHRTT 13722 QSGNLAR RSDHLSE QKANRTK RSDDLTR TSANLSR N/A 13743 RSDDLSK RSANLTR RSDDLTR RSDHLSE DKSNRKK N/A