SWAMINATHAN, SWARNALATHA,BENNAARS-EIDEN, ASSUMPTA A. G.,AHIMOU, FRANCOIS,FOLTZ, WILLIAM E.,ZHANG, YING
申请号：
CA2963415
公开号：
CA2963415A1
申请日:
2015.10.06
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A self-contained biological sterilization indicator is provided. The self-contained biological sterilization indicator includes an outer container having at least one liquid-impermeable wall and an interior volume； a sealed, openable, liquid-impermeable inner container enclosing a predetermined volume of an aqueous medium； a dry coating that comprises i) a plurality of viable test microorganisms useful to detect exposure to an oxidative sterilant and ii) an effective amount of a sterilant-resistance modulator； and a pathway that permits vapor communication between the interior volume and an atmosphere outside the outer container. The inner container and the dry coating are disposed in the interior volume. The modulator comprises an amino acid. The effective amount causes an increase in sensitivity of the test microorganisms to the oxidative sterilant relative to an otherwise-identical dry coating that lacks the effective amount.
