PURPOSE: A composition using Stichopus japonicus Orange extract is provided to suppress generation of NO(nitric oxide), inflammatory cytokines such as TNF-alpha and IL-6, COS-2(clooxygenase-2). CONSTITUTION: An anti-inflammatory composition contains Stichopus japonicus Orange extract as an active ingredient. The Stichopus japonicus Orange extract is isolated using alcohol of 1-5 carbon atoms, acetone, ethylacetate, ether, methylene chloride, chloroform, n-alkane of 5-10 carbon atoms, or mixture thereof. A composition of iNOS inhibition contains the Stichopus japonicus Orange extract as an active ingredient. A composition of COX-2 inhibition contains the Stichopus japonicus Orange extract as an active ingredient. An anti-cancer composition contains the Stichopus japonicus Orange extract as an active ingredient. The composition is a pharmaceutical composition or food composition.본 발명은 항염증제 조성물 및 항암제 조성물을 개시한다. 구체적으로 본 발명은 홍해삼 추출물을 이용한 항염증제 조성물 및 항암제 조성물을 개시한다.
