Disclosed is a method of concentrating a composition comprising galactosycerebrosidase and/or functionally equivalent parts and analogues hereof, said method comprising: a) centrifugation and/or filtration of a composition comprising galactosycerebrosidase and/or functionally equivalent parts and analogues hereof b) concentrating the supernatant or retentate, respectively, obtained from step a) c) obtaining from the concentrated supernatant or retentate of step b) an isotonic solution comprising galactosycerebrosidase, and d) formulating the isotonic solution for injection, said galactosycerebrosidase comprises an amino acid selected from the group consisting of: i) an amino acid sequence as defined by SEQ ID NO: 24 ii) a functionally equivalent analogue of an amino acid sequence as defined in i), the amino acid sequence of said analogue being at least 75% identical to an amino acid sequence as defined in i), wherein said functionally equivalent analogue of an amino acid sequence ins tep ii) have at least 50% of the activity of the natural enzyme.
