A system and method for providing a comprehensive overall health assessment is disclosed. A health assessment system (10) includes first and second support structures (14, 16) oriented in a vertical fashion and spaced apart from one another to define a scanning area (18) configured to receive a subject to be scanned, an x-ray imaging system (34, 36) incorporated into the first and second support structures (14, 16) and configured to acquire x-ray image data from the subject in a standing position, and at least one additional data acquisition device (28, 47, 48, 50, 52, 54) configured to acquire health related data from the subject. The health assessment system (10) also includes a computer (42) programmed to receive the x-ray image data and the health related data and generate a diagnostic output based on the x-ray image data and the health related data, the diagnostic output comprising at least one of a health related diagnosis and a recommendation for future action.