The present invention provides methods for preventing, treating, and/or managing cancer, the method comprising administering to a subject in need thereof therapeutically effective amount of sodium meta arsenite that reduces or eliminates drug resistant cancer stem cell populations as well as drug resistant mature cancer cells.本發明提供用於預防、治療及/或管控癌症的方法,該方法包含將治療有效量之亞砷酸鈉投與有其需要的對象,以減少或消滅抗藥性癌症幹細胞群以及抗藥性成熟癌細胞。