An object of the present invention is to provide an adsorbent for oral administration that eliminates the crispness in the oral cavity of fine granules of an adsorbent for oral administration, reduces the administration volume compared to capsules, and is easy to take. is there. The subject is a tablet-type composition for oral administration comprising 65% by weight or more of a particulate substance as an active ingredient and one or more additives, wherein (a) the particulate substance is added to water. It does not show solubility or swelling, has a distortion rate of 2% or less when subjected to a pressure of 2 MPa, and has a crushing strength of 5 MPa or more. (B) One tablet-type composition for oral administration is provided. The above-mentioned additive for particle preparation contains a total of 1% by weight or more with respect to the tablet-type composition for oral administration, and the additive for particle preparation contains 1% by weight of the aqueous solution or aqueous dispersion on the fluororesin plane. The solution for oral administration can be solved by forming a thin film when 0.5 mL is dropped and dried by heating.本発明の目的は、経口投与用吸着剤の細粒剤における口腔内のジャリジャリ感を解消し、カプセル剤と比較して投与ボリュームを減らし、そして服用しやすい経口投与用吸着剤を提供することである。前記課題は、有効成分として６５重量％以上の粒子状物質、及び１つ以上の添加剤からなる、錠剤型の経口投与用組成物であって、（ａ）前記粒子状物質が、水への溶解性及び膨潤性を示さず、２ＭＰａの圧力を受けた場合の歪率が２％以下であり、そして圧壊強度が５ＭＰａ以上であり、（ｂ）前記錠剤型経口投与用組成物が、１つ以上の粒子製剤用添加剤を、錠剤型経口投与用組成物に対して合計１重量％以上含み、前記粒子製剤用添加剤が、その１重量％の水溶液又は水分散液をフッ素樹脂平面上に０．５ｍＬ滴下し加熱乾燥した場合、薄膜を形成すること、を特徴とする経口投与用組成物によって解決することができる。
