GABELLIERI, EMANUELE,GUBA, WOLFGANG,HILPERT, HANS,MAUSER, HARALD,MAYWEG, ALEXANDER V.,ROGERS-EVANS, MARK,ROMBACH, DIDIER,THOMAS, ANDREW,WOLTERING, THOMAS,WOSTL, WOLFGANG
申请号：
CA2822783
公开号：
CA2822783A1
申请日:
2012.03.15
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention relates to 1,4-Oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
