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CATIONIC siRNA, SYNTHESIS AND USE FOR RNA INTERFERENCE
专利权人:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
发明人:
JEAN PAUL BEHR,MITSUHARA KOTERA,NADEGE PFENDER,JEAN SERGE REMY
申请号:
FR0800492
公开号:
FR2926818B1
申请日:
2008.01.30
申请国别(地区):
FR
年份:
2012
代理人:
摘要:
The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.
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