The present disclosure relates generally to pharmaceutical compositions comprising an active ingredient and a stabilizing agent, wherein the active ingredient is desmopressin or a pharmaceutically acceptable salt thereof, and wherein the stabilizing agent is one or more gums. The present disclosure further relates to methods of increasing the stability of a pharmaceutical composition comprising desmopressin or a pharmaceutically acceptable salt thereof as an active ingredient； methods for preparing orally disintegrating films comprising desmopressin or a pharmaceutically acceptable salt thereof and orally disintegrating films prepared thereby； and methods of treating or preventing nocturnal enuresis or nocturnal polyuria by administering stabilized pharmaceutical compositions comprising desmopressin or a pharmaceutically acceptable salt thereof as an active ingredient.
