Simon Bailey,Benjamin Joseph Burke,Michael Raymond Collins,Jingrong Jean Cui,Judith Gail Deal,Robert Louis Hoffman,Qinhua Huang,Ted William Johnson,Robert Steven Kania,John Charles Kath,Phuong Thi Quy
申请号:
US13786106
公开号:
US08680111B2
申请日:
2013.03.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to compounds of formula (Φ)as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.