COMPOSITIONS DESTINÉES À L'ADMINISTRATION D'ARNT SOUS LA FORME DE NANOPARTICULES ET PROCÉDÉ D'UTILISATION ASSOCIÉ

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专利权人:

The Board of Regents of The University of Texas System

发明人:

THOMAS, Philip, J.,SIEGWART, Daniel, J.,JOHNSON, Arthur, E.,TORRES, Michael, J.,MILLER, Jason, B.

申请号：

EP17800042

公开号：

EP3458074A4

申请日:

2017.05.16

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

In some aspects, the present disclosure provides a nanoparticle composition comprising tRNA and an aminolipid delivery compound. The aminolipid delivery compound may be a dendrimer, dendron, or dendritic lipid, a polymer such as a polyamide or polyester, or a lipid with one or more hydrophobic components. In some embodiments, these compositions may be administered to a patient to treat a genetic disease or disorder such as cystic fibrosis, Duchene muscular dystrophy, or cancer.

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