Jean Bemis;Pui Yee Ng;Chi B. Vu;Michael Jirousek;Walter Joseph Lunsmann;Jeremy S. Disch
发明人:
Jean Bemis,Jeremy S. Disch,Michael Jirousek,Walter Joseph Lunsmann,Pui Yee Ng,Chi B. Vu
申请号：
US12891667
公开号：
US08247565B2
申请日:
2010.09.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
