Inhibitors of CRL4 ubiquitin ligase and uses thereof

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专利权人:

Cornell University

发明人:

Zhou, Pengbo,Warren, J. David

申请号：

AU2013305824

公开号：

AU2013305824A1

申请日:

2013.08.21

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The invention is directed to a method of treating a cancer in an animal and a method of increasing DNA repair activity in an animal. The methods comprise administering to an animal in need thereof an effective amount of a small molecule substance that interferes with the activity of CUL4A, such as a 1,3-benzoxathiol-2-one compound, a pyridine thione compound, a 2,6-diamino-4-thiopyran-3,5-dicarbonitrile compound, or a 1,2,4-triazole-3-thiol compound.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/