ANAND, RAJAN,APGAR, JAMES M.,BIFTU, TESFAYE,CHEN, PING,CHU, LIN,COLANDREA, VINCENT J.,DONG, GUIZHEN,DROPINSKI, JAMES F.,FENG, DANQING,HICKS, JACQUELINE D.,JIANG, JINLONG,KIM, ALEXANDER J.,LEAVITT, KEN
申请号:
CA2826649
公开号:
CA2826649C
申请日:
2012.02.23
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Novel compounds of structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.