Abraham Shaked,Bao-Li Chang,Brendan Keating,Toumy Guettouche
申请号：
US16365194
公开号：
US20190313957A1
申请日:
2019.03.26
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to the discovery that the expression levels of some microRNAs (miRNAs) can use a diagnostic signature to predict transplant outcomes in a transplant recipient. Thus, in various embodiments described herein, the methods of the invention relate to methods of diagnosing a transplant subject for acute rejection such as acute cellular rejection (ACR), methods of predicting a subject's risk of having or developing ACR and methods of assessing in a subject the likelihood of a successful or failure minimization of immunosuppression therapy (IST) dosage from standard ranges.
