Hubbell, Jeffrey A.,Wang, Ruyi,Wilson, D. Scott,Nagler, Cathryn R.,Plunkett, Catherine
申请号：
AU2018255269
公开号：
AU2018255269A1
申请日:
2018.04.17
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Provided herein are polymer materials that find use in, for example, delivery of short-chain fatty acids. In particular, polymers are provided that form stable nanoscale structures and release their payload, for example, by cleavage of a covalent bond (e.g., via hydrolysis or enzymatic cleavage). The polymers are useful, for example, for delivery of payloads (e.g., SCFAs) to the intestine for applications in health and treatment of disease, and have broad applicability in diseases linked to changes in the human microbiota including inflammatory, autoimmune, allergic, metabolic, and central nervous system diseases, among others.
