IMMUNOGENIC POLYPEPTIDE COMPOSED OF TUMOR ANTIGEN-DERIVED OPTIMIZED CRYPTIC PEPTIDES, AND USES THEREOF

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专利权人:

VAXON BIOTECH

发明人:

KOSMATOPOULOS, KONSTANTINOS,CORNET, SEBASTIEN

申请号：

CA2634480

公开号：

CA2634480C

申请日:

2005.12.23

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

The present invention pertains to the field of anti-cancer vaccines. More particularly, the invention concerns an optimized polypeptide, which comprises three cryptic tumor peptides with enhanced immunogenicity and comprises the amino acids sequence YLQVNSLQTVYLEYRQVPVYLEEITGYL, for use in an anti-cancer vaccine. Nucleic acids encoding such a polypeptide, as well as complexes and dendritic cells engineered with this polypeptide or a nucleic acid encoding it, are also part of the invention.

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http://www.ckcest.cn/home/