Animal and an agent for the prophylaxis or treatment of stress urinary incontinence, which comprises an agent for the prophylaxis or treatment of stress urinary incontinence which comprises a substance that activates 5-HT 2C receptor serotonin, a substance that stimulates the androgen binding site a method of screening for stress urinary incontinence agent for the prophylaxis or treatment, which is characterized by increasing the abdominal pressure by electrical stimulation of nerves that govern it or sit-ups, to measure the (leak point pressure) leak point pressure at this time provide.セロトニン5-HT2C受容体を活性化する物質を含有してなる腹圧性尿失禁の予防・治療剤、アンドロゲン結合部位を刺激する物質を含有してなる腹圧性尿失禁の予防・治療剤及び動物の腹筋もしくはそれを支配する神経を電気刺激して腹圧を上昇させ、この時の漏出時圧(leak point pressure)を測定することを特徴とする腹圧性尿失禁予防・治療薬のスクリーニング方法を提供する。
