ALLEN, Shelley,ANDREWS, Steven W.,BLAKE, James F.,CONDROSKI, Kevin R.,HAAS, Julia,HUANG, Lily,JIANG, Yutong,KERCHER, Timothy,KOLAKOWSKI, Gabrielle R.,SEO, Jeongbeob
申请号：
MEP20177
公开号：
ME02583B
申请日:
2012.05.09
申请国别(地区):
ME
年份:
2017
代理人:
摘要：
or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R1, R2, Ra, Rb, Rc, Rd, X, Y, B, and Ring C are as defined herein, and wherein the Y—B moiety and the NH—C(═X)—NH moiety are in the trans configuration, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
