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PROCESS FOR the PREPARATION OF A COMPOUND, COMPOUND, and, COMPOSITION
专利权人:
GE HEALTHCARE AS
发明人:
ANDREAS OLSSON,Christian Gløgård,Mikkel Thaning
申请号:
BR112015004580
公开号:
BR112015004580A2
申请日:
2013.09.17
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
1/1 Summary "Process for the Preparation of a Compound, Compound, and Composition" The present invention relates to a process for the preparation of ioforminol, an agent of contrast usable in x-ray imaging. more particularly, the invention relates to the preparation of ioforminol from a mixture of a compound comprising 1-formylamino-3,5-bis (2,3-bis (formyloxy) propan-1-ylcarbamoyl) ) -2,4,6-triodobenzene by a process comprising in situ hydrolysis and a bis-alkylation.1 / 1 resumo “processo para a preparaã‡ãƒo de um composto, composto, e, composiã‡ãƒoâ€� a presente invenã§ã£o se refere a um processo para a preparaã§ã£o de ioforminol, um agente de contraste utilizã¡vel na formaã§ã£o de imagem por raios x. mais particularmente, a invenã§ã£o se refere ã  preparaã§ã£o de ioforminol a partir de uma mistura de composto compreendendo 1- formilamino-3,5-bis(2,3-bis(formiloxi)propan-1-ilcarbamoil)-2,4,6- triodobenzeno por um processo compreendendo hidrã³lise in situ e uma bis- alquilaã§ã£o.
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