Provided is an antibody that recognizes and binds to carbonic anhydrase orantigen-bindingfragment, a nucleic acid molecule coding for the antibody or antigen-bindingfragment, avector carrying the nucleic acid molecule, a host cell including the nucleicacid molecule or thevector, and use of the antibody or antigen-binding fragment thereof in thealleviation, prevention,treatment or diagnosis of solid cancers.
