RETROVIRAL VECTORS CONTAINING A REVERSE ORIENTATION HUMAN UBIQUITIN C PROMOTER

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专利权人:

The Regents of the University of California

发明人:

Donald B. Kohn,Aaron Ross Cooper

申请号：

US15738545

公开号：

US20180185415A1

申请日:

2016.06.22

申请国别(地区):

US

年份:

2018

代理人:

摘要：

In certain embodiments a recombinant retroviral vector is provided where the vector comprises a human ubiquitin C (UBC) promoter operably linked to a transgene where the promoter and the transgene are in a reverse orientation so that the direction of transcription of the transgene from the promoter is oriented towards a 5′ long terminal repeat (LTR) of the vector.

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中国工程科技知识中心

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http://www.ckcest.cn/home/