Fastening devices are provided that are designed to effectively close tissueas well as instruments for applying the inventive fastening devices. The devicesare useful for closing tissue such as mucosa in the oral cavity, oropharynx, hypopharynx,laryngeal surfaces, oronasopharynx, or other mucosal tissues. In particular,uvulopalatopharyngoplasty (UPPP), uvulopalatal flap (UPF) technique, andtonsillectomy can be assisted using the inventive system. Embodiments alsoprovide methods of using the fastening devices and/or instruments, and kitsincluding the fastening devices.
