1. A bispecific antibody which specifically binds an activating T cells an antigen and a tumor antigen (TA), comprising first Fab-fragment and a second Fab-fragment where exchanged or variable regions, or constant regions between the heavy and light chains of the second Fab-fragment and wherein the bispecific antibody contains no Fc-domen.2. A bispecific antibody of claim 1, wherein the first fragment comprises at least one antigen binding site specific for the tumor antigen. and a second Fab-fragment comprises at least one antigen binding site specific for antigenu.3 activating T cells. A bispecific antibody according to claim. 1 wherein the activating of T-cell antigen is a CD3 T cell koretseptorny (CD3) antigen.4. A bispecific antibody according to claim. 1, where the N-end of the second Fab-fragment is coupled to the C-terminus of the first Fab-fragmenta.5. A bispecific antibody according to Claim. 1 further comprising a third Fab-fragment.6. A bispecific antibody of claim. 5, where the third Fab-fragment comprises at least one antigen binding site specific for tumor antigenu.7. A bispecific antibody of claim. 5, where the third Fab-fragment is coupled with the first Fab-fragmentom.8. A bispecific antibody according to claim. 7, where the C-terminus of the third Fab-fragment is coupled with N-end of the first Fab-fragmenta.9. A bispecific antibody of claim. 5, where the third Fab-fragment is coupled with a second Fab-fragmentom.10. A bispecific antibody according to claim. 9 where the end of the third N-Fab-fragment is coupled to the C-terminus of the first Fab-fragmenta.11. A bispecific antibody of claim. 5, where the Fab-fragments are connected through a peptide linker.12. A bispecific antibody of claim. 11 wherein the peptide linker is sobo1. Биспецифическое антитело, которое специфически связывает активирующий Т-клетки антиген и опухолевый антиген (ТА), содержащее первый Fab-фрагмент и второй Fab-фрагмент, где произведен обмен либо вариабельными областями,
