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CYTOTOXIC T CELL RESPONSE MODIFIERS
专利权人:
DEUTSCHES KREBSFORSCHUNGSZENTRUM
发明人:
Philipp Beckhove,Michael Boutros,Nisit Khandelwal,Marco Breinig
申请号:
US16004077
公开号:
US20180298388A1
申请日:
2018.06.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a compound selectively binding to a sensory receptor or selectively altering the expression of a sensory receptor for use in a method for treating or preventing a disease associated with a pathologic cellular cytotoxic T cell (CTL) response. Further, the invention relates to means for detecting a sensory receptor for use in a method for diagnosing cellular resistance against CTL response in a patient. The invention further embraces a method for determining the resistance of a cell against a CTL response in vitro and to a method for identifying agents that influence the response of cells to CTLs.
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