STYLES, MICHELLE LEANNE,ZENG, JUN,TREUTLEIN, HERBERT RUDOLF,WILKS, ANDREW FREDERICK,KLING, MARCEL ROBERT,BU, XIANYONG,BURNS, CHRISTOPHER JOHN
申请号：
CA2545427
公开号：
CA2545427C
申请日:
2005.01.12
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
A compound of the general formula (I) or pharmaceutically acceptable prodrugs,salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein Arepresents a variety of six membered nitrogen containing heterocyclic rings, Qis a bond, halogen, C1-4 alkyl, O, S, SO2, CO or CS and X1, X2, X3 and X4 areoptionally substituted by 9 specific substituents or one can be nitrogen.Compositions comprising a carrier and at least one compound of formula (I) arealso provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) andmethods of suppressing the immune system of a subject by administering acompound of formula (I).
