ROR1-SPECIFIC CHIMERIC ANTIGEN RECEPTORS (CAR) WITH HUMANIZED TARGETING DOMAINS

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专利权人:

JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG

发明人:

Michael HUDECEK,Andreas MADES

申请号：

US16607069

公开号：

US20200040058A1

申请日:

2018.04.27

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention relates to chimeric antigen receptors (CAR) with a humanized targeting domain specific to the antigen ROR1. The invention encompasses the polynucleotides, vectors encoding said CARs and the isolated cells expressing them at their surface, in particularly for their use in immunotherapy.

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