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Therapeutic agent for inflammatory bowel disease and TNF-α production inhibitor
专利权人:
Tomoko Takeda;Masaki Hashimoto;Manabu Suzuki;Miho Ono;Tetsuo Yano;Hideki Matsumoto;Tomohisa Okutsu;Hideki Suzuki
发明人:
Hideki Matsumoto,Tomohisa Okutsu,Tomoko Takeda,Hideki Suzuki,Tetsuo Yano,Masaki Hashimoto,Miho Ono,Manabu Suzuki
申请号:
US12491698
公开号:
US08168669B2
申请日:
2009.06.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed is an agent for use in the treatment or prevention of inflammatory bowel disease. Also disclosed is an agent for inhibiting the production of TNF-α. A therapeutic or prophylactic agent for inflammatory bowel disease comprising at least one amino acid selected from the group consisting of lysine, histidine, phenylalanine, methionine, tryptophan, glutamine, glycine, cysteine, cystine and threonine, the amino acid being administered at a dose of 0.1 to 4000 mg/kg per day; and a TNF-α production inhibitor comprising an amino acid selected from the group consisting of histidine, phenylalanine and tryptophan, the amino acid being administered at a dose of 0.1 to 4000 mg/kg per day.
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