Using specific administration protocols and dosage regimens, it has been found that 3,3 '', 4,4''-tetrahydroxy-2,2''-bipyridine-N, N''-dioxide compounds, A pharmaceutical composition suitable for use in a therapeutic method as well as a method for treating renal cancer by administering 4''-tetrahydroxy-2,2''-bipyridine-N, N''-dioxide (orelanin) is provided.특정 투여 프로토콜 및 약량 섭생을 이용하여, 3,3',4,4'-테트라하이드록시-2,2'-바이피리딘-N,N'-디옥시드 화합물, 특히, 3,3',4,4'-테트라하이드록시-2,2'-바이피리딘-N,N'-디옥시드 (오렐라닌)를 투여하여 신장 암 치료하는 방법 뿐만 아니라, 치료 방법에 사용하는데 적합한 약학 조성물이 제공된다.