STEINER, ANDRE,WAENERLUND POULSEN, HEIDI,JOLIBOIS, EMILIE,REWOLINSKI, MELISSA,GROSS, RALF,SHARP, EMMA,DUBAS-FISHER, FIONA,EBERLIN, ALEX
申请号：
CA3028207
公开号：
CA3028207A1
申请日:
2013.06.17
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to obeticholic acid: or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a FXR mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing HDL cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of obeticholic acid.
