Koji Nakamura,Hiroyuki Yanai,Toru Kanke,Naoya Tsurushita,Shankar Kumar
申请号：
US14045326
公开号：
US09303086B2
申请日:
2013.10.03
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides: antibodies specifically reacting against hDlk-1 and having anti-tumor activity in vivo (anti-hDlk-1 antibodies, and in particular, humanized anti-hDlk-1 antibodies) fragments of the antibodies hybridomas that produce the antibodies a complex of the antibody or antibody fragment and an agent a pharmaceutical composition, a tumor therapeutic agent, a tumor diagnostic agent and an agent for inducing apoptosis in tumor cells, each of which comprises the aforementioned antibody or the like a method for treating tumor, a method for detecting tumor, a method for inducing apoptosis in tumor cells, a kit for detecting and/or diagnosing tumor and a kit for inducing apoptosis in tumor cells, each of which comprises the use of the aforementioned antibody or the like etc.
