PROBLEM TO BE SOLVED: To contribute to prevention and treatment of arteriosclerosis, especially atherosclerosis of pulmonary artery by finding a medicine that inhibits expression of adhesion molecule in vascular endothelial cells enhanced in an arteriosclerosis nest and production of monocyte chemoattractant protein-1 and has a slight toxicity and adverse effect.SOLUTION: The inhibitor of expression of adhesion molecule in vascular endothelial cells and production of monocyte chemoattractant protein-1 comprises a glucosamine salt as an active ingredient.COPYRIGHT: (C)2008,JPO&INPIT【課題】動脈硬化巣で増強される血管内皮細胞での接着分子の発現及び単球遊走因子の産生を抑制し、毒性及び副作用の少ない薬剤を見いだし、動脈硬化とくにアテローム性粥状動脈硬化の予防及び治療に貢献すること。【解決手段】グルコサミン塩を有効成分とする血管内皮細胞における接着分子の発現抑制及び単球遊走因子の産生抑制剤。【選択図】なし
