POLYPEPTIDES RECOMBINÉS MEMBRES DE LA FAMILLE DES LIGANDS TNF AYANT UN DOMAINE DE LIAISON D'UN ANTICORPS ET LEURS UTILISATIONS

• 收藏
• 分享

专利权人:

Universität Stuttgart

发明人:

申请号：

EP12712584.7

公开号：

EP2694550B1

申请日:

2012.03.30

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention relates in general to the field of TNF ligand family members. In more detail the present invention relates to polypeptides comprising at least three components A, each of which comprises the sequence of a TNF homology domain (THD) of a TNF ligand family member, or a functional derivative thereof, and comprising at least one component B consisting of a VL region and a VH region linked directly to each other with a linker sequence L which has a length of <；12 amino acids. Furthermore, the present invention also relates to nucleic acids encoding such polypeptides and pharmaceutical compositions thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/