Provided is a method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding a HhH-GPD-related polypeptide, or a calnexin-related polypeptide. Also provided are plants having modulated expression of a nucleic acid encoding a HhH-GPD-related polypeptide, or a calnexin-related polypeptide, which plants have enhanced yield-related traits relative to control plants.
