Brian Zahler Bentz,Kevin J. Webb,Dergan Lin,Justin Alexander Patel
申请号：
US16554307
公开号：
US20200069238A1
申请日:
2019.08.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A system for spatially mapping neurons in brain tissue is disclosed which includes a source of light configured to be shone on a subject at a first wavelength causing emission of light at a second wavelength from generating calcium when one or more neurons are firing, an optical filter configured to allow passage of light having the second wavelength, an image capture device configured to capture images of the brain tissue at the second wavelength, and a processor with software configured to establish a spatial model for localizing one or more neurons where captured images are used to iteratively adjust parameters of the model to thereby minimize error between generated and captured images.
