MONOCLONAL ANTIBODIES WHICH BIND TO THE EXTRACELLULAR DOMAIN OF THE AXL RECEPTOR TYROSINE KINASE

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专利权人:

发明人:

HETTMANN, THORE,NIEWOHNER, JENS,RUHE, JENS,WIRTZ, PETER,SELLE, KERSTIN,ZWICK-WALLASCH, ESTHER,ROTHE, MIKE

申请号：

NZ58546508

公开号：

NZ585465A

申请日:

2008.11.12

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a monoclonal antibody, as defined in the complete specification, which binds to the extracellular domain of AXL and at least partially inhibits AXL activity. Also disclosed is the use of said monoclonal antibody for the manufacture of a pharmaceutical composition for the diagnosis, prevention or treatment of a hyperproliferative disease.

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