DEMOPULOS, GREGORY A.,SCHWAEBLE, HANS-WILHELM,DUDLER, THOMAS,TJOELKER, LARRY
申请号:
CA3018774
公开号:
CA3018774A1
申请日:
2017.03.31
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
In one aspect, the present invention provides methods for preventing, treating, reverting and/or delaying angiogenesis in a mammalian subject suffering from, or at risk for developing, an angiogenesis-dependent disease or condition, comprising administering to the subject an amount of a MASP-2 inhibitory agent effective to inhibit angiogenesis. In some embodiments of these aspects of the invention, the MASP-2 inhibitory agent is a MASP-2 antibody or fragment thereof.