The Wistar Institute Of Anatomy And Biology;The Trustees of The University of Pennsylvania;Inovio Pharmaceuticals, Inc.
发明人:
MUTHUMANI, Karuppiah,YAN, Jian,WEINER, David
申请号：
EP17851763
公开号：
EP3515482A4
申请日:
2017.09.19
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Disclosed herein is a composition comprising a recombinant nucleic acid sequence that encodes an antibody to a Zika viral antigen, and functional fragments thereof. The invention also relates to a composition comprising the combination of a first composition that elicits an immune response in a mammal against zika virus and a second composition comprising a recombinant nucleic acid sequence encoding an antibody, a fragment thereof, a variant thereof, or a combination thereof. In some instances, the nucleic acid molecule comprises a nucleotide sequence encoding an anti-ZIKV-Envelope (anti-ZIKV E) Protein antibody.
