An ophthalmic treatment system and method for performing therapy on target tissuein a patient's eye. A delivery system delivers treatment light to the patient'seye and a camera captures a live image of the patient's eye. Control electronicscontrol the delivery system, register a pre-treatment image of the patient'seye to the camera's live image (where the pre-treatment image includesa treatment template that identifies target tissue within the patient'seye), and verify whether or not the delivery system is aligned to the target tissuedefined by the treatment template. The control electronics control the deliverysystem to project the treatment light onto the patient's eye in responseto both an activation of a trigger device and the verification that the deliverysystem is aligned to the target tissue, as well as adjust delivery system alignmentto track eye movement.