Giovanni Pozzi,Paolo Ghetti,Gaetano Balsamo,Ettore Negri,Marco Alpegiani,Angelo Bedeschi,Roberta Pizzocaro
申请号:
US12615334
公开号:
US08247426B2
申请日:
2009.11.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed is a crystalline form of irinotecan hydrochloride (I) and processes for the preparation thereof from crude irinotecan hydrochloride or another polymorphic form of irinotecan. Said crystalline form is particularly suitable for industrial use, because it is easily filtered and possesses characteristics of high stability and purity.