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КАПСУЛЫ СО СТРУКТУРОЙ ЯДРО-ОБОЛОЧКА
专利权人:
ФИРМЕНИШ СА (CH)
发明人:
ДАРДЕЛЬ Грегори (CH),ЭРНИ Филипп (CH)
申请号:
RU2013157351/15
公开号:
RU2013157351A
申请日:
2012.06.01
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A process for preparing capsules with a core-shell structure, comprising the steps of: (i) mixing the solid active ingredient and / or an oily liquid active ingredient with a polymer material capable of forming a hydrogel shell around the active ingredient (s) (ii) producing a shell comprising hydrogel framework derived from the polymer lattice around the nucleus (iii) optional crosslinking the polymer lattice (iv) optionally introducing a crosslinked hydrogel shell core-shell in contact with the liquid redshestvennikom silica to promote the deposition of silica in the frame structure, which thus forms a composite coating of silicon dioxide interspersed at intervals reshetki.2 polymer. A method according to Claim. 1, wherein the liquid precursor comprises dimethyldiethoxysilane silica, sodium silicates, sodium silicate hydrates, TEOS or smesi.3. A method according to claim. 2, wherein the liquid precursor is a silicon dioxide TEOS, and the deposition step (iv) is carried out under acidic usloviyah.4. A method according to any one of the preceding claims, wherein the liquid precursor of silica is in the form of an aqueous solution, and the aqueous phase of the solvent present in the hydrogel frame partially or completely consumed during the hydrolysis and precipitation of the liquid precursor kremniya.5 dioxide. A method according to any one of claims. 1-3, wherein a surfactant veschestvo.6. A method according to any one of claims. 1-3, wherein the liquid precursor of silica before encapsulation was stirred with active ingredientom.7. Capsule core-sheath, wherein: (a) obol1. Способ получения капсулы со структурой ядро-оболочка, включающий стадии:(i) перемешивания твердого активного ингредиента и/или маслянистого жидкого активного ингредиента с полимерным материалом, способным образовывать гидрогелевую оболочку вокруг активного ингредиента (ингредиентов)(ii) получения оболочки, включающей гидрогелевый каркас, полученный из полимерной решетки вокруг ядра(iii) необяз
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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