Julita S. Imperial,Baldomero M. Olivera,Paul F. Alewood,Heinz Terlau,David J. Craik,Estuardo Lopez-Vera,Pradip K. Bandyopadhyay
申请号:
US12301827
公开号:
US09062118B2
申请日:
2007.06.06
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to relatively short peptides (termed J-Superfamily conotoxin peptides, J-conotoxins or J-conotoxin peptides herein), about 25 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds. The J-conotoxins are useful for treating disorders involving voltage gated ion channels and/or receptors.