UTILISATION D'ACAMPROSATE POUR MODULER L'ACTIVATION D'ERK 1-2 DANS DES MODÈLES ANIMAUX POUR SXF ET TSA ET INDIVIDUS CHEZ LESQUELS ON A DIAGNOSTIQUÉ LE SXF ET LE TSA
Indiana University Research and Technology Corporation
发明人:
申请号：
EP14854852.2
公开号：
EP3058371A4
申请日:
2014.10.14
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Studies in mouse models of Fragile X and preliminary studies in human youth demonstrate that ERK1/2 is biomarker useful to monitoring the treatment of people diagnosed with ASD. Results reported herein demonstrate that acamprosate has the ability to reduce levels of ERK1/2 activation associated with many of the symptoms of ASD. Accordingly, in addition to its utility as a diagnostic marker for ASD ERK1/2 activation levels can be used to monitory patients treated with acamprosate.
